Slows disease progression
Extends average time to kidney failure
RISK PREDICTION
Identification of patients at a high risk of disease progression earlier may improve outcomes1,2
Sustained proteinuria of >1g/day is the strongest modifiable predictor of a high risk of kidney disease progression1–5
Reducing proteinuria:2–4
Patients with proteinuria >1g/day are at a high risk for progression to end-stage kidney disease (ESKD)2
REDUCING PROTEINURIA IS ASSOCIATED WITH IMPROVED PATIENT OUTCOMES
FIND OUT MOREThe International Risk Prediction Tool for IgAN can help identify patients at high risk of disease progression6–8
International Risk Prediction Tool for IgAN can be used:7,8
The International Risk Prediction Tool for IgAN is recommended by the most recent KDIGO guidelines and uses a variety of clinical parameters to predict disease progression7,8
The MEST-C (mesangial and endocapillary hypercellularity, segmental sclerosis, interstitial fibrosis/tubular atrophy, and crescents) score is a histopathological scoring system for patients with IgAN. The MEST-C score should be determined at the time of biopsy and is an important practice point for the diagnosis of IgAN6